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United Nations member countries pledged for the first time on Wednesday to take steps to tackle the threat posed by drug-resistant superbugs in a coordinated effort to curb the spread of infections by pathogens that defy antimicrobial medicines. The pledge during the annual U.N. General Assembly in New York followed years of warnings by global health officials about the rise of drug-resistant infections, which threaten to wipe out all effective antibiotics and antifungal medicines, leaving the world vulnerable to simple infections that once could be easily cured.